Veratraldehyde → 138989-48-7

반응식

[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][C:8]#[N:9].[CH3:10][O:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[CH:15]=O>>[CH3:10][O:11][C:12]1[CH:13]=[C:14](/[CH:15]=[C:7](/[C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)\[C:8]#[N:9])[CH:17]=[CH:18][C:19]=1[O:20][CH3:21]

참가 물질

반응물 2

HCID 8419Veratraldehyde

HCID 75959Pyridine-2-acetonitrile

생성물 1

HCID 5467797138989-48-7수율 77.4%

실험 절차

2-Pyridineacetonitrile (1.18 g) was condensed with 3,4-dimethoxybenzaldehyde (1.66 g) through Method B (production step 2), to thereby yield the target product (yield: 2.06 g, 77%).

출처 및 근거

ORD 기록: ord-40122a29d6904270936d0dd12bfa1a43
출처 데이터셋: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08697742B2

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