Hydrochloric Acid → HCID 67226852, 화합물

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[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6](/[CH:12]=[C:13](/[C:16]2[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=2)\[C:14]#[N:15])[CH:7]=[CH:8][C:9]=1[O:10][CH3:11]>>[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6](/[CH:12]=[C:13](/[C:16]2[CH:17]=[N:18][CH:19]=[CH:20][CH:21]=2)\[C:14]#[N:15])[CH:7]=[CH:8][C:9]=1[O:10][CH3:11]

참가 물질

반응물 2

HCID 313Hydrochloric Acid

HCID 5468216(Z)-3-(3,4-dimethoxyphenyl)-2-pyridin-3-ylprop-2-enenitrile

생성물 1

HCID 67226852HCID 67226852, 화합물수율 99%

실험 절차

0.1N Hydrochloric acid (8.3 mL) was added to Compound 44 (200 mg) for dissolution, and purified water (5 mL) was added to the solution, followed by stirring at room temperature for 20 minutes. The reaction mixture was lyophilized, to thereby yield the target product (yield: 224 mg, 99%).

후처리

custompurified water (5 mL)
additionwas added to the solution

출처 및 근거

ORD 기록: ord-092d2958f5f94ff3b76d3d0f43164c33
출처 데이터셋: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08697742B2

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