Hydrochloric Acid → HCID 67227007, 화합물
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[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6](/[CH:12]=[C:13](/[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=2)\[C:14]#[N:15])[CH:7]=[CH:8][C:9]=1[O:10][CH3:11]>C(#N)C>[ClH:1].[CH3:2][O:3][C:4]1[CH:5]=[C:6](/[CH:12]=[C:13](/[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=2)\[C:14]#[N:15])[CH:7]=[CH:8][C:9]=1[O:10][CH3:11]참가 물질
4
실험 절차
0.1N Hydrochloric acid (4.1 mL) was added to Compound 45 (100 mg), and acetonitrile (20 mL) was added to the mixture, to thereby dissolve the mixture. The solution was stirred in the dark at room temperature for 1 hour, and the solvent was evaporated to dryness. The precipitated crystals were thoroughly dried, to thereby yield the target product (yield: 112 mg, 99%).
후처리
- additionwas added to the mixture
- dissolutionto thereby dissolve the mixture
- customthe solvent was evaporated to dryness
- customThe precipitated crystals were thoroughly dried
출처 및 근거
- ORD 기록
- ord-cd53d870db90480488f4595ac76ee0da
- 출처 데이터셋
- uspto-grants-2014_04
- 특허 번호
- US08697742B2
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