Hydrochloric Acid → 5-(1,1,2-Trifluoro-2-(perfluoropropoxy)ethoxy)isophthalic acid

HRID 2366507노트

반응식

HRID 2366507 반응식
[F:1][C:2]([F:31])([O:16][C:17]1[CH:18]=[C:19]([C:27]([O:29]C)=[O:28])[CH:20]=[C:21]([CH:26]=1)[C:22]([O:24]C)=[O:23])[CH:3]([F:15])[O:4][C:5]([F:14])([F:13])[C:6]([F:12])([F:11])[C:7]([F:10])([F:9])[F:8].[OH-].[K+].Cl>O>[F:1][C:2]([F:31])([O:16][C:17]1[CH:26]=[C:21]([C:22]([OH:24])=[O:23])[CH:20]=[C:19]([CH:18]=1)[C:27]([OH:29])=[O:28])[CH:3]([F:15])[O:4][C:5]([F:13])([F:14])[C:6]([F:11])([F:12])[C:7]([F:8])([F:10])[F:9]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 58426160Dimethyl 5-(1,1,2-trifluoro-2-(perfluoropropoxy)ethoxy)isophthalate

생성물 1

HCID 866753405-(1,1,2-Trifluoro-2-(perfluoropropoxy)ethoxy)isophthalic acid수율 85.9%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Dimethyl 5-(1,1,2-trifluoro-2-(perfluoropropoxy)ethoxy)isophthalate (47.6 g, 0.10 mol) was added to a solution of water (1.00 L) and KOH (206 g, 3.5 mol). The resulting solution was heated to reflux for about 48 hours. The reaction was cooled to room temperature and then acidified to a pH of about 1 with concentrated HCl. The precipitate material was filtered and then dried under vacuum for 4 days to give 38.51 g of product.

후처리

  1. temperatureThe resulting solution was heated
  2. temperatureto reflux for about 48 hours
  3. filtrationThe precipitate material was filtered
  4. customdried under vacuum for 4 days

출처 및 근거

ORD 기록
ord-7989048dce46449ea184bb1fc0150576
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08697831B2

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