Oxalyl chloride → 5-Cyano-furan-2-carboxylic acid [2'fluoro-5-(4-methyl-piperazin-1-yl)-biphenyl-2-yl]-amide

반응식

[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[C:13]([N+:14]([O-])=O)=[CH:12][CH:11]=[C:10]([N:17]2[CH2:22][CH2:21][N:20]([CH3:23])[CH2:19][CH2:18]2)[CH:9]=1.[C:24]([C:26]1[O:30][C:29]([C:31](O)=[O:32])=[CH:28][CH:27]=1)#[N:25].C(Cl)(=O)C(Cl)=O.CCN(C(C)C)C(C)C>[Pd].CO.ClCCl.CN(C=O)C>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:9]=[C:10]([N:17]2[CH2:22][CH2:21][N:20]([CH3:23])[CH2:19][CH2:18]2)[CH:11]=[CH:12][C:13]=1[NH:14][C:31]([C:29]1[O:30][C:26]([C:24]#[N:25])=[CH:27][CH:28]=1)=[O:32]