Hydrochloric Acid → 2-Aminobenzene-1,4-diol hydrochloride

HRID 2368067노트

반응식

HRID 2368067 반응식
[N+:1]([C:4]1[CH:9]=[C:8]([OH:10])[CH:7]=[CH:6][C:5]=1[OH:11])([O-])=O.[ClH:12]>[C].[Pd]>[ClH:12].[NH2:1][C:4]1[CH:9]=[C:8]([OH:10])[CH:7]=[CH:6][C:5]=1[OH:11]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 43139181,4-Benzenediol, 2-nitro-

생성물 1

HCID 136850472-Aminobenzene-1,4-diol hydrochloride

시약·촉매·용매 1

HCID 178418390HCID 178418390, 화합물촉매

실험 절차

A suspension of 2-nitrobenzene-1,4-diol (1.00 g) and 10% palladium carbon (containing water (50%), 1.00 g) in 1 M hydrochloric acid (13 mL) was stirred at room temperature for 5 hr under a hydrogen atmosphere. The reaction mixture was filtered, the filtrate was concentrated under reduced pressure, and the obtained solid was washed with ethyl acetate to give the title compound (949 mg).

후처리

  1. filtrationThe reaction mixture was filtered
  2. concentrationthe filtrate was concentrated under reduced pressure
  3. washthe obtained solid was washed with ethyl acetate

출처 및 근거

ORD 기록
ord-6fca3bfb201147458a9d136b374616c1
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08703758B2

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