Sodium borohydride → HCID 12536095, 화합물

HRID 236892노트

반응식

HRID 236892 반응식
[O:1]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[C:4](=[O:11])[CH:3]=[C:2]1[CH:12]=[O:13].[BH4-].[Na+]>CO>[OH:13][CH2:12][C:2]1[O:1][C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[C:4](=[O:11])[CH:3]=1

참가 물질

4

반응물 2

HCID 4311764Sodium borohydrideHCID 104196624-oxo-4H-chromene-2-carbaldehyde

생성물 1

HCID 12536095HCID 12536095, 화합물수율 55%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A mixture of 4H-1-benzopyran-4-one-2-carboxaldehyde (400 mg, 0.0023 m) and sodium borohydride (8.8 mg. 0.0023 m) in methanol (20 ml) was stirred at room temperature for 30 minutes. The solvent was removed at reduced pressure to give a white solid. The solid was washed with water, sucked dry, and recrystallized from ethanol to give white crystals (220 mg, 55%), m.p. 165°-167°.

후처리

  1. customThe solvent was removed at reduced pressure
  2. customto give a white solid
  3. washThe solid was washed with water
  4. customsucked dry
  5. customrecrystallized from ethanol

출처 및 근거

ORD 기록
ord-8d43d417ab5b4b19b0f78661905787b3
출처 데이터셋
uspto-grants-1979_06
특허 번호
US04158663

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