1-(3-Chlorophenyl)piperazine → 1-(3-Chlorophenyl)-4-(4-nitrophenyl)sulfonylpiperazine

HRID 237024

반응식

HRID 237024 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10](Cl)(=[O:12])=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2].[Cl:14][C:15]1[CH:16]=[C:17]([N:21]2[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]2)[CH:18]=[CH:19][CH:20]=1>C(N(CC)CC)C>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10]([N:24]2[CH2:23][CH2:22][N:21]([C:17]3[CH:18]=[CH:19][CH:20]=[C:15]([Cl:14])[CH:16]=3)[CH2:26][CH2:25]2)(=[O:12])=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2]

참가 물질

4

반응물 2

HCID 13551-(3-Chlorophenyl)piperazineHCID 74044-Nitrobenzenesulfonyl chloride

생성물 1

HCID 10197251-(3-Chlorophenyl)-4-(4-nitrophenyl)sulfonylpiperazine

시약·촉매·용매 1

HCID 8471Triethylamine용매

실험 절차

In the manner given in Example 1A, p-nitrobenzenesulfonyl chloride, 1-(m-chlorophenyl)piperazine, and triethylamine are stirred at reflux to give 1-[(p-nitrophenyl)sulfonyl]-4-(m-chlorophenyl)piperazine.

후처리

  1. temperatureat reflux

출처 및 근거

ORD 기록
ord-dd6266a2b2ba43b992466510e0d45622
출처 데이터셋
uspto-grants-1979_06
특허 번호
US04159331

연결된 노트

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