Hydrazine hydrate (1:1) → 6-(4-Fluorophenyl)-3-hydrazinyl-1,2,4-triazine

HRID 237097노트

반응식

HRID 237097 반응식
Cl[C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([F:14])=[CH:10][CH:9]=2)=[CH:6][N:7]=1.O.[NH2:16][NH2:17]>N1C=CC=CC=1>[NH:16]([C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][C:11]([F:14])=[CH:10][CH:9]=2)=[CH:6][N:7]=1)[NH2:17]

참가 물질

4

반응물 2

HCID 24654Hydrazine hydrate (1:1)HCID 213152193-Chloro-6-(4-fluorophenyl)-1,2,4-triazine

생성물 1

HCID 213152186-(4-Fluorophenyl)-3-hydrazinyl-1,2,4-triazine

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

A solution of 9.8 g. of 3-chloro-6-(p-fluorophenyl)-1,2,4-triazine in 125 ml. of pyridine is cooled to 0° C. and 15 ml. of hydrazine hydrate is added. The mixture is stirred at room temperature for one hour and then poured into icewater. The solid is recovered by filtration and washed with ethanol, giving 3-hydrazino-6-(p-fluorophenyl)-1,2,4-triazine as an orange solid.

후처리

  1. additionpoured into icewater
  2. filtrationThe solid is recovered by filtration
  3. washwashed with ethanol

출처 및 근거

ORD 기록
ord-c279d885aaa140f9bb11cee7ab004c31
출처 데이터셋
uspto-grants-1979_06
특허 번호
US04159375

반응 노트

불러오는 중…