Methyl (R)-(1-hydroxy-3-methylbutan-2-YL)carbamate → (4R)-4-(Propan-2-yl)-1,3-oxazolidin-2-one
반응식
CO[C:3]([NH:5][C@@H:6]([CH2:10][OH:11])[CH:7]([CH3:9])[CH3:8])=[O:4]>C1(C)C=CC=CC=1>[CH3:9][CH:7]([C@@H:6]1[CH2:10][O:11][C:3](=[O:4])[NH:5]1)[CH3:8]참가 물질
3
반응 조건
- 온도
- 150 °C
실험 절차
27.2 g (168.7 mmol) of the compound from Example V are dissolved in 400 ml of toluene and stirred under reflux in an oil bath at 150° C. while passing in nitrogen.
출처 및 근거
- ORD 기록
- ord-7518c1e32d2b4d4fadb76a3e57559c1e
- 출처 데이터셋
- uspto-grants-1992_03
- 특허 번호
- US05095006
반응 노트
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