Water → 3-benzyl-2-[(N-cyclohexylcarbamoyl)-imino]benzothiazole

HRID 2371703

반응식

HRID 2371703 반응식
[CH2:1]([N:8]1[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=2[S:10][C:9]1=[NH:17])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C([O-])(=O)CCCCCCCCCCC.C([O-])(=O)CCCCCCCCCCC.C([Sn+2]CCCC)CCC.[CH:55]1([N:61]=[C:62]=[O:63])[CH2:60][CH2:59][CH2:58][CH2:57][CH2:56]1.O>CC(C)=O>[CH2:1]([N:8]1[C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=2[S:10][C:9]1=[N:17][C:62](=[O:63])[NH:61][CH:55]1[CH2:60][CH2:59][CH2:58][CH2:57][CH2:56]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

6

반응물 4

HCID 962WaterHCID 18502Cyclohexyl isocyanateHCID 6775663-Benzyl-2-iminobenzothiazoleHCID 9809426Di-n-butyldilauryltin

생성물 1

HCID 544673103-benzyl-2-[(N-cyclohexylcarbamoyl)-imino]benzothiazole수율 73.1%

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

To a solution of 1.8 g of 3-benzyl-2-iminobenzothiazole and a catalytic amount of dibutyltin dilaurate in 30 ml of acetone was added 0.95 g of cyclohexyl isocyanate dropwise. After seven hours, the reaction mixture was poured into approximately 100 ml of water. The crystals precipitated were collected by filtering to thereby obtain 2.0 g of the objective compound.

후처리

  1. customThe crystals precipitated
  2. customwere collected
  3. filtrationby filtering

출처 및 근거

ORD 기록
ord-0e6b3d4aa3dc4c98960b65ff1deb1b73
출처 데이터셋
uspto-grants-1992_03
특허 번호
US05095025

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