Phosphorus sulfide (P2S5) → HCID 19903350, 화합물

HRID 2372374노트

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HRID 2372374 반응식
[CH3:1][CH:2]1[CH2:6][NH:5][C:4](=O)[CH:3]1[C:8]([O:10][CH2:11][CH3:12])=[O:9].P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:14]>C1C=CC=CC=1>[CH3:1][CH:2]1[CH2:6][NH:5][C:4](=[S:14])[CH:3]1[C:8]([O:10][CH2:11][CH3:12])=[O:9]

참가 물질

4

반응물 2

HCID 14817Phosphorus sulfide (P2S5)HCID 19903390HCID 19903390, 화합물

생성물 1

HCID 19903350HCID 19903350, 화합물수율 146.6%

시약·촉매·용매 1

HCID 241Benzene용매

반응 조건

온도
50 °C

실험 절차

2.5 g of ethyl 4-methyl-2-oxopyrrolidine-3-carboxylate and 3.4 g of phosphorus pentasulfide were added to 50 ml of benzene and stirred at 50° C. for 1 hour. After cooling, the insoluble matters were filtered off and the filtrate was concentrated. The residue was purified by silica gel chromatography to thereby give 2.1 g of the title compound as an oily product.

후처리

  1. temperatureAfter cooling
  2. filtrationthe insoluble matters were filtered off
  3. concentrationthe filtrate was concentrated
  4. customThe residue was purified by silica gel chromatography

출처 및 근거

ORD 기록
ord-ecc0947e65be4fd4b37b52f5debd7034
출처 데이터셋
uspto-grants-1992_03
특허 번호
US05098919

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