U 84935 → HCID 70059045, 화합물

HRID 2372716노트

반응식

HRID 2372716 반응식
[CH:1]1([C:4]2[O:8][N:7]=[C:6]([C:9]3[N:10]=[CH:11][N:12]4[C:21]5[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=5[C:15]5=[N:22][CH2:23][CH2:24][N:14]5[C:13]=34)[N:5]=2)[CH2:3][CH2:2]1.[C:25]([OH:34])(=[O:33])[C@@H:26]([C@H:28]([C:30]([OH:32])=[O:31])[OH:29])[OH:27]>ClCCl>[C:30]([C@@H:28]([C@H:26]([C:25]([OH:34])=[O:33])[OH:27])[OH:29])([OH:32])=[O:31].[CH:1]1([C:4]2[O:8][N:7]=[C:6]([C:9]3[N:10]=[CH:11][N:12]4[C:21]5[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=5[C:15]5=[N:22][CH2:23][CH2:24][N:14]5[C:13]=34)[N:5]=2)[CH2:3][CH2:2]1

참가 물질

4

반응물 2

HCID 131796U 84935HCID 444305L-Tartaric acid

생성물 1

HCID 70059045HCID 70059045, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Equimolar amounts of 5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2,3-dihydrodiimidazo[1,5-a:1',2'-c]quinazoline (0.64 g) and L-tartaric acid (0.30 g) was stirred in dichloromethane (25 ml) until a clear solution was obtained. The solvent was removed by evaporation in vacuo and the residue was triturated with isopropyl alcohol. The crystalline precipitate was filtered off and recrystallized from ethanol yielding the title compound as pale crystals, m.p. 160°-163° C. (Compound 41).

후처리

  1. customwas obtained
  2. customThe solvent was removed by evaporation in vacuo
  3. customthe residue was triturated with isopropyl alcohol
  4. filtrationThe crystalline precipitate was filtered off
  5. customrecrystallized from ethanol yielding the title compound as pale crystals, m.p. 160°-163° C. (Compound 41)

출처 및 근거

ORD 기록
ord-3ff57096c9694f3d9418f2558d2626f8
출처 데이터셋
uspto-grants-1992_03
특허 번호
US05100895

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