alpha,alpha'-Dichloro-p-xylene → Phosphonic acid, P,P'-(1,4-phenylenebis(methylene))bis-, P,P,P',P'-tetraethyl ester

HRID 2373137

반응식

HRID 2373137 반응식
Cl[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9]Cl)=[CH:5][CH:4]=1.[P:11]([O:18][CH2:19][CH3:20])([O:15][CH2:16][CH3:17])[O:12]CC>>[C:6]1([CH2:9][P:11](=[O:12])([O:15][CH2:16][CH3:17])[O:18][CH2:19][CH3:20])[CH:7]=[CH:8][C:3]([CH2:2][P:11](=[O:12])([O:18][CH2:19][CH3:20])[O:15][CH2:16][CH3:17])=[CH:4][CH:5]=1

참가 물질

3

반응물 2

HCID 12171alpha,alpha'-Dichloro-p-xyleneHCID 31215Triethyl phosphite

생성물 1

HCID 78303Phosphonic acid, P,P'-(1,4-phenylenebis(methylene))bis-, P,P,P',P'-tetraethyl ester

반응 조건

온도
180 °C

실험 절차

A mixture of α,α′-dichloro-p-xylene (20 g, 0.114 mol) and triethyl phosphite (60 ml) was refluxed at 180° C. overnight. 80 ml of hexanes was added, and white crystals were formed immediately. Then the mixture was cooled at 0° C., and the product was collected, washed three times with 40 ml of hexanes and isolated in 94.4% (40.8 g) yield.

후처리

  1. customwhite crystals were formed immediately
  2. temperatureThen the mixture was cooled at 0° C.
  3. customthe product was collected
  4. washwashed three times with 40 ml of hexanes
  5. customisolated in 94.4% (40.8 g)
  6. customyield

출처 및 근거

ORD 기록
ord-06046a032b19462a939e55a60924d148
출처 데이터셋
uspto-grants-2008_12
특허 번호
US07459106B2

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