반응식
Cl[C:2]1[CH:3]=[CH:4][C:5](=[O:9])[N:6]([CH3:8])[N:7]=1.[CH3:10][C:11]1[CH:17]=[C:16](B2OC(C)(C)C(C)(C)O2)[CH:15]=[C:14]([CH3:27])[C:12]=1[NH2:13]>>[NH2:13][C:12]1[C:14]([CH3:27])=[CH:15][C:16]([C:2]2[CH:3]=[CH:4][C:5](=[O:9])[N:6]([CH3:8])[N:7]=2)=[CH:17][C:11]=1[CH3:10]참가 물질
3
반응 조건
- 온도
- 60 °C
실험 절차
The title compound is prepared from 6-chloro-2-methylpyridazin-3(2H)-one and 2,6-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline following a procedure analogous to that described in Step 2 of Intermediate 62. The mixture is stirred for 12 hours at 60° C. LC (method 9): tR=0.78 min; Mass spectrum (ESI+): m/z=230 [M+H]+.
출처 및 근거
- ORD 기록
- ord-83d92abcc37f4bf3b06641409de7fa4a
- 출처 데이터셋
- uspto-grants-2014_02
- 특허 번호
- US08642585B2
연결된 노트
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