3-Iodophthalic acid → 3-Iodophthalic anhydride

HRID 2377014

반응식

HRID 2377014 반응식
[I:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:4]([C:5]([OH:7])=O)[C:3]=1[C:11]([OH:13])=[O:12]>C(OC(=O)C)(=O)C>[I:1][C:2]1[C:3]2[C:11](=[O:12])[O:13][C:5](=[O:7])[C:4]=2[CH:8]=[CH:9][CH:10]=1

참가 물질

3

반응물 1

HCID 2382313-Iodophthalic acid

생성물 1

HCID 2820713-Iodophthalic anhydride수율 65.2%

시약·촉매·용매 1

HCID 7918Acetic Anhydride용매

실험 절차

A solution of 3-iodophthalic acid (0.9 g, 3.08 mmol) in acetic anhydride (5 mL) was heated to reflux under nitrogen overnight. After cooling, the solvent was removed in vacuo and the residue purified by trituration with ethanol to give 4-iodo-2-benzofuran-1,3-dione (0.55 g, 65%).

후처리

  1. temperatureto reflux under nitrogen overnight
  2. temperatureAfter cooling
  3. customthe solvent was removed in vacuo
  4. customthe residue purified by trituration with ethanol

출처 및 근거

ORD 기록
ord-06b41cd4add44d28838ce483980247c8
출처 데이터셋
uspto-grants-2008_12
특허 번호
US07468393B2

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