3-Iodophthalic acid → 3-Iodophthalic anhydride
반응식
[I:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:4]([C:5]([OH:7])=O)[C:3]=1[C:11]([OH:13])=[O:12]>C(OC(=O)C)(=O)C>[I:1][C:2]1[C:3]2[C:11](=[O:12])[O:13][C:5](=[O:7])[C:4]=2[CH:8]=[CH:9][CH:10]=1참가 물질
3
실험 절차
A solution of 3-iodophthalic acid (0.9 g, 3.08 mmol) in acetic anhydride (5 mL) was heated to reflux under nitrogen overnight. After cooling, the solvent was removed in vacuo and the residue purified by trituration with ethanol to give 4-iodo-2-benzofuran-1,3-dione (0.55 g, 65%).
후처리
- temperatureto reflux under nitrogen overnight
- temperatureAfter cooling
- customthe solvent was removed in vacuo
- customthe residue purified by trituration with ethanol
출처 및 근거
- ORD 기록
- ord-06b41cd4add44d28838ce483980247c8
- 출처 데이터셋
- uspto-grants-2008_12
- 특허 번호
- US07468393B2
반응 노트
불러오는 중…