Dimethylformamide dimethyl acetal → HCID 86602114, 화합물

HRID 2377047노트

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HRID 2377047 반응식
[CH3:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][N:5]=[C:4]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:3]=1.CO[CH:18](OC)[N:19]([CH3:21])[CH3:20]>CN(C=O)C>[CH3:18][N:19]([CH3:21])/[CH:20]=[CH:1]/[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][N:5]=[C:4]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:3]=1

참가 물질

4

반응물 2

HCID 78373Dimethylformamide dimethyl acetalHCID 44549262HCID 44549262, 화합물

생성물 1

HCID 86602114HCID 86602114, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

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온도
90 °C

실험 절차

A mixture of ethyl 4-methyl-5-nitropyridine-2-carboxylate (39.5 g, 0.19 mol), dimethylformamide-dimethylacetal (DMF-DMA) (30.6 g, 0.26 mol, 1.35 eq) in DMF (470 mL) was heated to 90° C. for 30 min. The solvent was removed in vacuo. The residue (78 g) was used without further purification in the next step.

후처리

  1. customThe solvent was removed in vacuo
  2. customThe residue (78 g) was used without further purification in the next step

출처 및 근거

ORD 기록
ord-b4dc6674623440ea8dd4409b12dd4645
출처 데이터셋
uspto-grants-2008_12
특허 번호
US07468375B2

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