L-Tartaric acid → 2-amino-N-(2-(3a-(R)-benzyl-3-oxo-2,3,3a,4,6,7-hexahydro-pyrazolo[4,3-c]pyridin-5-yl)-1-(R)benzyloxymethyl-2-oxo-ethyl)isobutyramide
반응식
[NH2:1][C:2]([CH3:43])([CH3:42])[C:3]([NH:5][CH:6]([CH2:31][O:32][CH2:33][C:34]1[CH:39]=[CH:38][C:37](F)=[CH:36][C:35]=1F)[C:7](=[O:30])[N:8]1[CH2:13][CH2:12][C:11]2=[N:14][N:15](CC(F)(F)F)[C:16](=[O:17])[C:10]2([CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26]N=2)[CH2:9]1)=[O:4].[C:44](O)(=O)[C@@H]([C@H](C(O)=O)O)O>>[NH2:1][C:2]([CH3:42])([CH3:43])[C:3]([NH:5][C@H:6]([CH2:31][O:32][CH2:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)[C:7]([N:8]1[CH2:13][CH2:12][C:11]2=[N:14][NH:15][C:16](=[O:17])[C@:10]2([CH2:23][C:24]2[CH:44]=[CH:26][CH:27]=[CH:28][CH:29]=2)[CH2:9]1)=[O:30])=[O:4]참가 물질
3
반응물 2
생성물 1
실험 절차
2-amino-N-(1-(2,4-difluoro-benzyloxymethyl)-2-oxo-2-(3-oxo-3a-pyridin-2-ylmethyl-2-(2,2,2-trifluoro-ethyl)-2,3,3a,4,6,7-hexahydro-pyrazolo[4,3-c]pyridin-5-yl)-ethyl)-2-methyl-propionamide (U.S. Pat. No. 6,110,932) or its L-tartaric acid salt.