1-Phenylpiperazine → alpha-{[1-(4-Phenylpiperazinyl)]methyl}benzeneacetic acid

HRID 2379693노트

반응식

HRID 2379693 반응식
[C:1]1([N:7]2[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:13]([OH:23])(=[O:22])[C:14]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[CH2:15]>C(O)C>[C:1]1([N:7]2[CH2:12][CH2:11][N:10]([CH2:15][CH:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[C:13]([OH:23])=[O:22])[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

4

반응물 2

HCID 70961-PhenylpiperazineHCID 68114Atropic acid

생성물 1

HCID 19433570alpha-{[1-(4-Phenylpiperazinyl)]methyl}benzeneacetic acid

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

1-Phenylpiperazine and atropic acid in ethanol is heated under reflux for 18h, cooled to room temperature, and evaporated in vacuo. The solid is triturated with acetone to give the title product.

후처리

  1. customevaporated in vacuo
  2. customThe solid is triturated with acetone

출처 및 근거

ORD 기록
ord-c44b4576b93d468db51b1b96c49107ff
출처 데이터셋
uspto-grants-1994_11
특허 번호
US05364849

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