Acetic Acid → HCID 15729150, 화합물
반응식
C([NH:4][C:5]1[S:6][C:7]([S:10]([C:12]2[CH:17]=[CH:16][C:15]([NH2:18])=[CH:14][CH:13]=2)=[O:11])=[CH:8][N:9]=1)(=O)C.Cl.C(O)(=O)C.C(=O)([O-])[O-].[Na+].[Na+]>O>[NH2:4][C:5]1[S:6][C:7]([S:10]([C:12]2[CH:17]=[CH:16][C:15]([NH2:18])=[CH:14][CH:13]=2)=[O:11])=[CH:8][N:9]=1참가 물질
6
실험 절차
A mixture of 2-acetylamino-5-(4-aminophenylsulfinyl)thiazole (5.0 g) in a mixture of aqueous 6N-hydrochloric acid (10 ml) and acetic acid (35 ml) was refluxed for 3.5 hours with stirring. The reaction mixture was diluted with water and adjusted to pH 8 using aqueous sodium carbonate under ice cooling. The precipitates were collected by filtration, washed with water and dried in vacuo to give 2-amino-5-(4-aminophenylsulfinyl)thiazole (4.5 g, yield: 100%).
후처리
- temperaturewas refluxed for 3.5 hours
- filtrationThe precipitates were collected by filtration
- washwashed with water
- customdried in vacuo
출처 및 근거
- ORD 기록
- ord-afd0e188f3524c0d8d68ffefce70fa69
- 출처 데이터셋
- uspto-grants-1994_11
- 특허 번호
- US05369107
반응 노트
불러오는 중…