Formaldehyde → HCID 178430444, 화합물
반응식
C([N:20]1[CH:24]=[C:23]([CH:25]([CH3:28])[CH2:26][NH2:27])[N:22]=[CH:21]1)(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.[CH2:29]=O>Cl>[CH3:28][CH:25]1[CH2:26][NH:27][CH2:29][CH:24]2[N:20]=[CH:21][NH:22][CH:23]12참가 물질
4
반응 조건
- 온도
- 95 °C
실험 절차
3.2 g 2-(1-trityl-1H-imidazol-4-yl)-propylamine is suspended in aqueous HCl (1 N). After the addition of 2.9 mL formaldehyde the mixture is heated to 95° C. with stirring. After 5 h it is cooled to RT, suction filtered to remove the precipitate formed and the solvent is eliminated in vacuo. This crude product is used in the following reaction step without further purification.
후처리
- temperatureAfter 5 h it is cooled to RT
- filtrationsuction filtered
- customto remove the precipitate
- customformed
출처 및 근거
- ORD 기록
- ord-e73142bd30874a93aca363f3d2483565
- 출처 데이터셋
- uspto-grants-2012_09
- 특허 번호
- US08258129B2
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