N-Hydroxyphthalimide → Cyclopentadecanone

HRID 23831

반응식

HRID 23831 반응식
[OH:1]N1[C:6](=O)[C:5]2=[CH:8][CH:9]=[CH:10][CH:11]=[C:4]2[C:3]1=[O:12].[O-]O.[C:15]1([CH:21](C)[CH3:22])C=[CH:19][CH:18]=[CH:17][CH:16]=1.[CH2:24]1[CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>>[CH:3]1([OH:12])[CH2:4][CH2:11][CH2:10][CH2:9][CH2:8][CH2:5][CH2:6][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:21][CH2:22]1.[C:24]1(=[O:1])[CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1.[CH2:24]1[CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1

참가 물질

6

반응물 3

HCID 10665N-HydroxyphthalimideHCID 67525CyclopentadecaneHCID 53627471Cumen hydroperoxide

생성물 3

HCID 10409CyclopentadecanoneHCID 67525CyclopentadecaneHCID 107327Cyclopentadecanol

실험 절차

2 mmol of N-hydroxyphthalimide and 4 mmol of cumene hydroperoxide are added at a temperature of 130° C. to 200 mmol of cyclopentadecane in a round-bottomed flask having an attached reflux condenser. Air is passed at approximately 15 l/h through the reaction mixture for 8 hours at said temperature. Cyclopentadecanol is obtained at a selectivity of 19% and cyclopentadecanone at a selectivity of 48%, at a cyclopentadecane conversion rate of 46%.

후처리

  1. temperaturean attached reflux condenser

출처 및 근거

ORD 기록
ord-b4316f5813ca4db3abf2bfd09b53bc97
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06852893B2

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