홈MCP워크벤치Skills
홈워크벤치알림마이페이지
llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
  1. 홈
  2. /반응

Acrylic Acid → HCID 18979457, 화합물

HRID 2392589
노트
인쇄 미리보기

반응식

HRID 2392589 반응식
C1(N=C=NC2CCCCC2)CCCCC1.[CH:16]([C:18]1[CH:23]=[CH:22][C:21]([C:24]2[CH:29]=[CH:28][C:27]([O:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][OH:39])=[CH:26][CH:25]=2)=[CH:20][CH:19]=1)=[O:17].[C:40](O)(=[O:43])[CH:41]=[CH2:42]>CN(C)C1C=CN=CC=1.ClCCl>[CH:16]([C:18]1[CH:23]=[CH:22][C:21]([C:24]2[CH:29]=[CH:28][C:27]([O:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][O:39][C:40](=[O:43])[CH:41]=[CH2:42])=[CH:26][CH:25]=2)=[CH:20][CH:19]=1)=[O:17]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 3

HCID 6581Acrylic AcidHCID 10868DicyclohexylcarbodiimideHCID 18979506HCID 18979506, 화합물

생성물 1

HCID 18979457HCID 18979457, 화합물수율 56.4%

시약·촉매·용매 2

HCID 142844-(Dimethylamino)pyridine촉매HCID 6344Dichloromethane용매

실험 절차

2.9 g of N,N'-dicyclohexylcarbodiimide were added within 5 minutes while stirring to a solution of 3.8 g of 4-formyl-4'-(8-hydroxyoctyloxy)biphenyl, 0.9 g of acrylic acid and 0.05 g of 4-(dimethylamino)pyridine in 25 ml of dichloromethane. The reaction mixture was stirred overnight, filtered and then concentrated. Chromatography of the residue on silica gel with hexane/ethyl acetate (vol. 8:2) and recrystallization from ethyl alcohol of the fractions which were pure according to thin-layer chromatography gave 2.5 g of 4-formyl-4'-(8-acryloyloxyoctyloxy)biphenyl.

후처리

  1. filtrationfiltered
  2. concentrationconcentrated
  3. customChromatography of the residue on silica gel with hexane/ethyl acetate (vol. 8:2) and recrystallization from ethyl alcohol of the fractions which

출처 및 근거

ORD 기록
ord-e8dc56b416c84bff844df391b51b7311
출처 데이터셋
uspto-grants-1998_09
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US05800733

반응 노트

불러오는 중…

이 페이지에서참가 물질실험 절차후처리출처 및 근거반응 노트