Dodecylamine → HCID 18980712, 화합물

HRID 2392916노트

반응식

HRID 2392916 반응식
[CH2:1]([NH2:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].Cl[CH2:15][CH:16]([OH:36])[CH2:17][N:18]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[CH2:19][CH:20]([OH:23])[CH2:21]Cl>C1(C)C(C)=CC=CC=1>[OH:36][CH:16]([CH2:17][N:18]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[CH2:19][CH:20]([OH:23])[CH2:21][NH:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])[CH2:15][NH:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

참가 물질

4

반응물 2

HCID 13583DodecylamineHCID 189807231,1'-(Dodecylazanediyl)bis(3-chloropropan-2-ol)

생성물 1

HCID 18980712HCID 18980712, 화합물수율 49.4%

시약·촉매·용매 1

HCID 7237O-Xylene용매2회

반응 조건

온도
80 °C

실험 절차

A reactor was charged with 286.3 g (1.54 moles) of dodecylamine and 90 g of xylene, and the contents were heated to 80° C. To the contents, a solution with 57 g (0.15 mole) of N,N-bis(3-chloro-2-hydroxypropyl)dodecylamine dissolved in 50 g of xylene was added dropwise over 1.5 hours. The resultant mixture was aged further for 4 hours. Thereafter, xylene was distilled off under reduced pressure, and unreacted dodecylamine was then distilled off at 100° C. and 0.5 mmHg. The residue was added with 500 ml of hexane and 2000 ml of acetone to be dissolved therein. The solution was then subjected to extraction and washing with a mixture of 500 ml of xylene and 500 ml of 5% aqueous sodium hydroxide. Thereafter, a xylene layer was taken out and concentrated, thereby obtaining 49.5 g (yield: 48%) of 15,19-dihydroxy-17-dodecyl-13,17,21-triazatritriacontane represented by the following formula. ##STR10##

후처리

  1. additionwas added dropwise over 1.5 hours
  2. distillationThereafter, xylene was distilled off under reduced pressure, and unreacted dodecylamine
  3. distillationwas then distilled off at 100° C.
  4. additionThe residue was added with 500 ml of hexane and 2000 ml of acetone
  5. dissolutionto be dissolved
  6. extractionThe solution was then subjected to extraction
  7. washwashing with a mixture of 500 ml of xylene and 500 ml of 5% aqueous sodium hydroxide
  8. concentrationconcentrated

출처 및 근거

ORD 기록
ord-b928c7e3fe0243fa921325ee854becf2
출처 데이터셋
uspto-grants-1998_09
특허 번호
US05801270

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