4-(3,4-Dichlorophenyl)-3-buten-2-one → HCID 53715145, 화합물

HRID 2395597노트

반응식

HRID 2395597 반응식
[BH4-].[Na+].[Cl:3][C:4]1[CH:5]=[C:6]([CH:11]=[CH:12][C:13](=[O:15])[CH3:14])[CH:7]=[CH:8][C:9]=1[Cl:10]>C(O)C>[Cl:3][C:4]1[CH:5]=[C:6]([CH:11]=[CH:12][CH:13]([OH:15])[CH3:14])[CH:7]=[CH:8][C:9]=1[Cl:10]

참가 물질

4

반응물 2

HCID 3265634-(3,4-Dichlorophenyl)-3-buten-2-oneHCID 4311764Sodium borohydride

생성물 1

HCID 53715145HCID 53715145, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

2.25 g (0.0599 mol) of NaBH4 are added portionwise at room temperature to a suspension of 39.2 g (0.182 mol) of 4-(3,4-dichlorophenyl)-3-buten-2-one in 900 ml of ethanol and the mixture is stirred overnight at room temperature. The mixture is concentrated under vacuum, taken up in water, extracted with methylene chloride, washed with water, dried over sodium sulphate, filtered and evaporated under vacuum. The product obtained is used without subsequent purification in the following stage. Yd.: 35.2 g (89%)

후처리

  1. concentrationThe mixture is concentrated under vacuum
  2. extractionextracted with methylene chloride
  3. washwashed with water
  4. dry with materialdried over sodium sulphate
  5. filtrationfiltered
  6. customevaporated under vacuum
  7. customThe product obtained
  8. customis used without subsequent purification in the following stage

출처 및 근거

ORD 기록
ord-cf60c2991c014088927f434838cef0e5
출처 데이터셋
uspto-grants-1996_02
특허 번호
US05489592

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