Cyclohexylamine → HCID 21437961, 화합물

HRID 2397417노트

반응식

HRID 2397417 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:13]=[CH:12][C:11]([C:14](=[O:20])[CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.C1(N)CCCCC1.C(OCC)(=O)C>CO>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:13]=[CH:12][C:11]([CH:14]([OH:20])[CH2:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1

참가 물질

5

반응물 3

HCID 7965CyclohexylamineHCID 8857Ethyl AcetateHCID 230052374-(3'-Chloro-4-biphenylyl)-4-oxo-butyric acid

생성물 1

HCID 21437961HCID 21437961, 화합물수율 65%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Prepared analogous to Example 25 from 4-(3'-chloro-4-biphenylyl)-4-oxo-butyric acid. Melting point of the cyclohexylamine salt: 160°-161° C. (from ethyl acetate by addition of methanol). Yield: 65% of theory.

출처 및 근거

ORD 기록
ord-55c3bd4b006e46339b7dcb3bd8e6eb76
출처 데이터셋
uspto-grants-1977_05
특허 번호
US04021479

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