1-Bromopropane → HCID 21436737, 화합물

HRID 2397924노트

반응식

HRID 2397924 반응식
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][N:8]=[CH:9]2)([O-:3])=[O:2].[Br:14][CH2:15][CH2:16][CH3:17]>C(O)C>[Br-:14].[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][N+:8]([CH2:15][CH2:16][CH3:17])=[CH:9]2)([O-:3])=[O:2]

참가 물질

4

반응물 2

HCID 78401-BromopropaneHCID 690855-Nitroisoquinoline

생성물 1

HCID 21436737HCID 21436737, 화합물수율 48.1%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

5-Nitroisoquinoline (10.0 g) and 1-bromopropane (7.8 g) were refluxed in ethanol (200 ml) for five days. On cooling to room temperature, a yellow powdery precipitate formed. This was collected by vacuum filtration and purified by recrystallization from ethanol to yield 8.2 g of the desired 5-nitro-2-n-propylisoquinolinium bromide as yellow, crystalline needles, m.p. 206.5°-209.5° C.

후처리

  1. customa yellow powdery precipitate formed
  2. filtrationThis was collected by vacuum filtration
  3. custompurified by recrystallization from ethanol

출처 및 근거

ORD 기록
ord-2cc1ce367f0e4f38a9172926aa45249f
출처 데이터셋
uspto-grants-1977_05
특허 번호
US04022900

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