N-bromobutanimide → Ethyl 2-Methyl-3-furoate

HRID 2398649

반응식

HRID 2398649 반응식
[C:1]([C:4](=[CH:10][CH3:11])[C:5]([O:7][CH2:8][CH3:9])=[O:6])(=[O:3])[CH3:2].BrN1C(=O)CCC1=O>C(Cl)(Cl)(Cl)Cl>[CH3:2][C:1]1[O:3][CH:11]=[CH:10][C:4]=1[C:5]([O:7][CH2:8][CH3:9])=[O:6]

참가 물질

4

반응물 2

HCID 67184N-bromobutanimideHCID 53941670Ethyl 2-acetylbut-2-enoate

생성물 1

HCID 261900Ethyl 2-Methyl-3-furoate수율 24%

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

A mixture of 3.12 g (0.02 mole) ethyl 2-acetyl-2-butenoate and 3.56 g (0.02 mole) N-bromosuccinimide in 50 ml of carbon tetrachloride was heated at reflux for 19 hours. After cooling, the insoluble succinimide was removed by filtration and the solution concentrated by rotary evaporation. Distillation of the crude product gave 0.73 g (24%) of ethyl 2-methyl-3-furoate, bp 87°-9° C. (20 mm).

후처리

  1. temperaturewas heated
  2. temperatureat reflux for 19 hours
  3. temperatureAfter cooling
  4. customthe insoluble succinimide was removed by filtration
  5. concentrationthe solution concentrated by rotary evaporation
  6. distillationDistillation of the crude product

출처 및 근거

ORD 기록
ord-9b92a50ab88542f7ab03d1dc7dab9998
출처 데이터셋
uspto-grants-1977_05
특허 번호
US04025537

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