N-bromobutanimide → HCID 12452841, 화합물
반응식
[C:1]([C:4](=[CH:10][CH2:11][CH:12]([CH3:14])[CH3:13])[C:5]([O:7][CH2:8][CH3:9])=[O:6])(=[O:3])[CH3:2].BrN1C(=O)CCC1=O>C(Cl)(Cl)(Cl)Cl>[CH:12]([C:11]1[O:3][C:1]([CH3:2])=[C:4]([C:5]([O:7][CH2:8][CH3:9])=[O:6])[CH:10]=1)([CH3:13])[CH3:14]참가 물질
4
실험 절차
A mixture of 3.97 g (0.02 mole) ethyl 2-acetyl-5-methyl-2-hexenoate and 3.55 g (0.02 mole) N-bromosuccinimide in 50 ml of carbon tetrachloride was heated at reflux for 2.5 hours. After cooling, the succinimide was removed by filtration and the solution concentrated by rotary evaporation. Distillation of the crude product gave 3.33 g (85% ) of ethyl 5-isopropyl-2-methyl-3-furoate, bp 112°-114° C. (11 mm).
후처리
- temperaturewas heated
- temperatureat reflux for 2.5 hours
- temperatureAfter cooling
- customthe succinimide was removed by filtration
- concentrationthe solution concentrated by rotary evaporation
- distillationDistillation of the crude product
출처 및 근거
- ORD 기록
- ord-0728c37e81da434bb73d2191524a42e2
- 출처 데이터셋
- uspto-grants-1977_05
- 특허 번호
- US04025537
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