2,2-Dimethyl-1,3-dioxane-4,6-dione → HCID 21883483, 화합물

HRID 240202노트

반응식

HRID 240202 반응식
[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=O.CC1(C)O[C:16](=O)[CH2:15][C:13](=[O:14])[O:12]1>O>[NH:1]1[C:2]2[C:3](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:15]([C:13]([OH:14])=[O:12])[CH2:16]1

참가 물질

4

반응물 2

HCID 162492,2-Dimethyl-1,3-dioxane-4,6-dioneHCID 682552-Aminobenzaldehyde

생성물 1

HCID 21883483HCID 21883483, 화합물수율 71.3%

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
75 °C

실험 절차

2-Aminobenzaldehyde (84.1 mg, 0.69 mmol) and Meldrum's acid (100 mg, 0.69 mmol) were combined in H2O (1 mL). The solution was stirred at 75° C. for 2 h. After cooling to room temperature, the precipitate was filtered and dried at suction to give 86.2 mg of 1,2-dihydro-quinoline-3-carboxylic acid with a yield of 66%.

후처리

  1. temperatureAfter cooling to room temperature
  2. filtrationthe precipitate was filtered
  3. customdried at suction

출처 및 근거

ORD 기록
ord-5ef52b34e05c4e4fa46203c4166b41d0
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08642788B2

반응 노트

불러오는 중…