Isobutyraldehyde → HCID 178422251, 화합물
반응식
Cl.N[C@@H]1CC[C@H](OC2C=C3C(=CC=2C)C(=O)NC=C3)CC1.C(=O)C(C)C.C(N[C@@H]1CC[C@H](OC2C=C3C(=CC=2C)C(=O)NC=C3)CC1)C.[CH2:49]([NH:53][CH:54]1[CH2:59][CH2:58][CH:57]([O:60][C:61]2[CH:62]=[C:63]3[C:68](=[CH:69][C:70]=2[CH3:71])[C:67](=[O:72])[NH:66][CH:65]=[CH:64]3)[CH2:56][CH2:55]1)[CH:50]([CH3:52])[CH3:51]>>[CH2:49]([NH:53][C@@H:54]1[CH2:55][CH2:56][C@H:57]([O:60][C:61]2[CH:62]=[C:63]3[C:68](=[CH:69][C:70]=2[CH3:71])[C:67](=[O:72])[NH:66][CH:65]=[CH:64]3)[CH2:58][CH2:59]1)[CH:50]([CH3:52])[CH3:51]참가 물질
5
실험 절차
From 0.2 (0.65 mmol) of 6-(cis-4-amino-cyclohexyloxy)-7-methyl-2H-isoquinolin-1-one hydrochloride (138) and isobutyraldehyde were obtained analogous to example 139 151 mg of 6-(4-isobutylamino-cyclohexyloxy)-7-methyl-2H-isoquinolin-1-one. Rt=1.10 min (Method A). Detected mass: 329.20 (M+H+).