Hydrochloric Acid → [2,4'-Bipyridine]-3-carboxylic acid dihydrochloride

HRID 240393노트

반응식

HRID 240393 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([O:9]CC)=[O:8])[C:2]=1[C:12]1[CH:17]=[CH:16][N:15]=[CH:14][CH:13]=1.[ClH:18]>>[ClH:18].[ClH:18].[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([OH:9])=[O:8])[C:2]=1[C:12]1[CH:17]=[CH:16][N:15]=[CH:14][CH:13]=1

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 46317743Ethyl [2,4'-bipyridine]-3-carboxylate

생성물 1

HCID 84819756[2,4'-Bipyridine]-3-carboxylic acid dihydrochloride

실험 절차

A solution of ethyl 2,4′-bipyridine-3-carboxylate (14.1 g) in 6 N hydrochloric acid (200 mL) was heated under reflux overnight. The solvent was evaporated under reduced pressure, to the obtained residue was added toluene, and the solvent was again evaporated under reduced pressure to give the title compound (16.4 g).

후처리

  1. temperatureunder reflux overnight
  2. customThe solvent was evaporated under reduced pressure, to the obtained residue
  3. additionwas added toluene
  4. customthe solvent was again evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-0985a229539f494894619095dc9732a6
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08648079B2

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