2-Amino-5-nitrobenzoic acid → HCID 178526470, 화합물
반응식
[NH2:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=O.C(O)(=O)C.[CH:18](N)=[NH:19]>COC(O)C>[N+:11]([C:8]1[CH:7]=[C:3]2[C:2](=[CH:10][CH:9]=1)[N:1]=[CH:18][N:19]=[C:4]2[OH:6])([O-:13])=[O:12]참가 물질
4
반응 조건
- 온도
- 115 °C
실험 절차
A mixture of 2-amino-5-nitrobenzoic acid (1000 g, 5 mol) and formamidine acetate (1000 g, 10 mol) were dissolved in methoxyethanol (4 L) and heated to 115° C. for 16 hours. After cooling the mixture to room temperature, ice water (5 L) was added and the mixture was stirred for 30 minutes before collecting the product (125 g, 14%) by filtration.
후처리
- temperatureAfter cooling the mixture to room temperature
- custombefore collecting the product (125 g, 14%)
- filtrationby filtration
출처 및 근거
- ORD 기록
- ord-c6eaa425e0df4e24ab878d970d8aa4c3
- 출처 데이터셋
- uspto-grants-2014_02
- 특허 번호
- US08648087B2
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