HCID 58413223, 화합물 → HCID 58413003, 화합물

HRID 240599노트

반응식

HRID 240599 반응식
[F:1][C:2]1[CH:3]=[CH:4][C:5]([N+:14]([O-])=O)=[C:6]([CH:13]=1)[O:7][C@@H:8]1[CH2:12][CH2:11][O:10][CH2:9]1>CO.[Ni]>[F:1][C:2]1[CH:3]=[CH:4][C:5]([NH2:14])=[C:6]([O:7][C@@H:8]2[CH2:12][CH2:11][O:10][CH2:9]2)[CH:13]=1

참가 물질

4

반응물 1

HCID 58413223HCID 58413223, 화합물

생성물 1

HCID 58413003HCID 58413003, 화합물

시약·촉매·용매 2

HCID 935Nickel촉매HCID 887Methanol용매

실험 절차

To a solution of (R)-3-(5-fluoro-2-nitrophenoxy)tetrahydrofuran (1.8 g) in MeOH (60.0 ml) was added Ra/Ni (200.0 mg), the mixture hydrogenated at room temperature. The catalyst was filtered off and the filtrate was concentrated.

후처리

  1. customhydrogenated at room temperature
  2. filtrationThe catalyst was filtered off
  3. concentrationthe filtrate was concentrated

출처 및 근거

ORD 기록
ord-e3a4a21eea60440e913ef549c8f7f5e3
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08648068B2

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