Ethyl Acetate → 3-(S)-Methyl-pentanedioic acid mono-(2-trimethylsilanyl-ethyl) ester
반응식
[CH3:1][Si:2]([CH3:17])([CH3:16])[CH2:3][CH2:4][O:5][C:6](=[O:15])[CH2:7][C@@H:8]([CH3:14])[CH2:9][C:10]([O:12]C)=[O:11].O.[OH-].[Li+].[Cl-].[NH4+].C(OCC)(=O)C>C(O)(C)C.O>[CH3:17][Si:2]([CH3:1])([CH3:16])[CH2:3][CH2:4][O:5][C:6](=[O:15])[CH2:7][C@@H:8]([CH3:14])[CH2:9][C:10]([OH:12])=[O:11]참가 물질
7
실험 절차
To the solution of 3-(S)-Methyl-pentanedioic acid methyl ester 2-trimethylsilanyl-ethyl ester in iso-propanol and water was added lithium hydroxide monohydrate and stirred for two hours at RT. The reaction mixture was treated with saturated ammonium chloride and ethyl acetate. The product was purified by column chromatography.
후처리
- customThe product was purified by column chromatography
출처 및 근거
- ORD 기록
- ord-8a7c15a82800408a8c70620c287dc923
- 출처 데이터셋
- uspto-grants-2014_08
- 특허 번호
- US08809382B2
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