Hydrochloric Acid → HCID 178487304, 화합물
반응식
C[O:2][C:3]1[C:4]2[N:5]([CH:15]=[N:16][N:17]=2)[C:6]2[C:11]([N:12]=1)=[CH:10][C:9]([O:13][CH3:14])=[CH:8][CH:7]=2.Cl>C(O)(=O)C>[OH:2][C:3]1[C:4]2[N:5]([CH:15]=[N:16][N:17]=2)[C:6]2[C:11]([N:12]=1)=[CH:10][C:9]([O:13][CH3:14])=[CH:8][CH:7]=2참가 물질
4
실험 절차
A mixture consisting of 1.6 g. (0.0069 mole) of 4,7-dimethoxy-[1,2,4]triazolo[4,3-a]quinoxaline, 16 ml. of 1N hydrochloric acid and 48 ml. of glacial acetic acid was refluxed for a period of three hours. Upon completion of this step, the reaction mixture was poured over ice and filtered. The recovered product was then collected on the filter funnel and washed with diethyl ether to ultimately afford 1.19 g. (80%) of pure 4-hydroxy-7-methoxy-[1,2,4]triazolo[4,3-a]quinoxaline, m.p. >250° C.
후처리
- additionUpon completion of this step, the reaction mixture was poured over ice
- filtrationfiltered
- customThe recovered product was then collected on the filter funnel
- washwashed with diethyl ether to ultimately afford 1.19 g
출처 및 근거
- ORD 기록
- ord-c27d6e8398a14604bb6b5a43ffc4e544
- 출처 데이터셋
- uspto-grants-1985_01
- 특허 번호
- US04495187
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