Hydrochloric Acid → Hydrochloric Acid

HRID 2414410노트

반응식

HRID 2414410 반응식
[CH2:1]([O:8][C:9]1[CH:16]=[CH:15][C:12]([C:13]#[N:14])=[CH:11][C:10]=1[O:17][CH2:18][CH2:19][NH:20]C(OC(C)(C)C)=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:28]>O1CCOCC1>[ClH:28].[NH2:20][CH2:19][CH2:18][O:17][C:10]1[CH:11]=[C:12]([CH:15]=[CH:16][C:9]=1[O:8][CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[C:13]#[N:14]

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 226451464-Benzyloxy-3-[2-(t-butoxycarbonylamino)ethoxy]benzonitrile

생성물 2

HCID 313Hydrochloric AcidHCID 226451763-(2-Aminoethoxy)-4-benzyloxybenzonitrile

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

3.4 g (9.2 mmol) of 4-benzyloxy-3-[2-(t-butoxycarbonylamino)ethoxy]benzonitrile was dissolved in 40 ml of 4 N solution of hydrogen chloride in dioxane, and the obtained solution was stirred overnight. The solvent was evaporated to obtain hydrochloride of the crude title compound.

후처리

  1. customThe solvent was evaporated

출처 및 근거

ORD 기록
ord-6ccd5f608d5d43d5b8e922188263b6b5
출처 데이터셋
uspto-grants-2004_11
특허 번호
US06812231B2

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