Acetic Anhydride → HCID 20269005, 화합물

HRID 2417851노트

반응식

HRID 2417851 반응식
[OH:1][CH:2]1[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[NH:7][C:6](=[O:14])[CH2:5][CH2:4][CH2:3]1.[C:15](OC(=O)C)(=[O:17])[CH3:16]>>[C:15]([O:1][CH:2]1[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[NH:7][C:6](=[O:14])[CH2:5][CH2:4][CH2:3]1)(=[O:17])[CH3:16]

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 20269010HCID 20269010, 화합물

생성물 1

HCID 20269005HCID 20269005, 화합물

실험 절차

A solution of 6-hydroxy-3,4,5,6-tetrahydro-1-benzazocin-2-(1H)one (9.2 g) in acetic anhydride (200 ml) is maintained at 80° C. for 3 hours. The reaction mixture is cooled to room temperature and the solvents removed under reduced pressure. Ether (300 ml) is added, and their resulting solution washed with water (150 ml) and dried over magnesium sulfate. The solvent is removed under reduced pressure to give 6-acetoxy-3,4,5,6-tetrahydro-1-benzazocin-2(1H)-one.

후처리

  1. customthe solvents removed under reduced pressure
  2. additionEther (300 ml) is added
  3. customtheir resulting solution
  4. washwashed with water (150 ml)
  5. dry with materialdried over magnesium sulfate
  6. customThe solvent is removed under reduced pressure

출처 및 근거

ORD 기록
ord-4d58a634ffca4eb583c91d2dbaa4c7f9
출처 데이터셋
uspto-grants-1984_09
특허 번호
US04470988

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