Acetic Anhydride → HCID 13577653, 화합물

HRID 2418236노트

반응식

HRID 2418236 반응식
[Br:1][C:2]1[C:11]([F:12])=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][CH:6]([CH3:13])[NH:7]2.[C:14](OC(=O)C)(=[O:16])[CH3:15]>>[C:14]([N:7]1[C:8]2[C:3](=[C:2]([Br:1])[C:11]([F:12])=[CH:10][CH:9]=2)[CH2:4][CH2:5][CH:6]1[CH3:13])(=[O:16])[CH3:15]

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 128968175-Bromo-6-fluoro-2-methyl-1,2,3,4-tetrahydroquinoline

생성물 1

HCID 13577653HCID 13577653, 화합물

실험 절차

The 5-bromo-6-fluoro-1,2,3,4-tetrahydroquinaldine intermediate of Formula IV is reacted in step (3) with acetic anhydride to provide the novel intermediate 1-acetyl-5-bromo-6-fluoro-1,2,3,4-tetrahydroquinaldine of Formula V. The reaction is conducted by heating the reaction mixture, for example, using a steam bath.

출처 및 근거

ORD 기록
ord-fdde1e3c023e4e5492f6ac0ce1d12e8e
출처 데이터셋
uspto-grants-1984_09
특허 번호
US04472407

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