2-Oxo-4-phenylbutyric acid → HCID 22822708, 화합물
반응식
O=[C:2]([CH2:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:3]([OH:5])=[O:4].[NH2:14][C@H:15]([C:18]([N:20]1[CH2:27][CH2:26][CH2:25][C@H:21]1[C:22]([OH:24])=[O:23])=[O:19])[CH2:16][OH:17].C([BH3-])#N.[Na+]>>[C:3]([CH:2]([NH:14][C@H:15]([C:18]([N:20]1[CH2:27][CH2:26][CH2:25][C@H:21]1[C:22]([OH:24])=[O:23])=[O:19])[CH2:16][OH:17])[CH2:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)([OH:5])=[O:4]참가 물질
4
실험 절차
In the manner described in example 24, 2-oxo-4-phenylbutyric acid and L-serinyl-L-proline are condensed in the presence of sodium cyanoborohydride to yield N-(1-carboxy-3-phenylpropyl)-L-serinyl-L-proline.
출처 및 근거
- ORD 기록
- ord-5c295b465fd84a489b6c077190dbda9e
- 출처 데이터셋
- uspto-grants-1984_09