Formamide → 6-Amino-5-nitroso-2-pyridin-3-ylpyrimidin-4-ylamine

HRID 2418683

반응식

HRID 2418683 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:15]=[C:14]3[C:10]([N:11]=C[NH:13]3)=[C:9]([NH2:16])[N:8]=2)[CH:2]=1.C(N)(=N)C1C=CC=NC=1.C(N)=[O:27]>>[NH2:16][C:9]1[C:10]([N:11]=[O:27])=[C:14]([NH2:13])[N:15]=[C:7]([C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)[N:8]=1

참가 물질

4

반응물 3

HCID 713FormamideHCID 2020433-PyridinecarboxamidineHCID 178508302HCID 178508302, 화합물

생성물 1

HCID 2309336-Amino-5-nitroso-2-pyridin-3-ylpyrimidin-4-ylamine

실험 절차

Taylor et al [J. Am. Chem. Soc. 81, 2442-8 (1959)] show, inter alia, the preparation of 2-(3-pyridinyl)-9H-purin-6-amine by heating the nicotinamidine salt of isonitrosomalonitrile in formamide to produce 4,6-diamino-5-nitroso-2-(3-pyridinyl)pyrimidine and heating the reaction mixture containing said 5-nitroso compound and formamide with a mixture of formic acid and sodium dithionite dihydrate to produce said 2-(3-pyridinyl)-9H-purin-6-amine, for which no use is indicated.

출처 및 근거

ORD 기록
ord-0e5d6867f6dc4277803d67e3ebc1a509
출처 데이터셋
uspto-grants-1984_09
특허 번호
US04473571

연결된 노트

불러오는 중…