Methyl Nicotinate → HCID 97181391, 화합물

HRID 2418880노트

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HRID 2418880 반응식
COC(=O)c1cccnc1.O=S(O)C(F)F.[Zn]>CC(C)(C)OO.ClCCl.O.O=C(O)C(F)(F)F>COC(=O)c1ccc(C(F)F)nc1.COC(=O)c1cccnc1C(F)F.COC(=O)c1cnccc1C(F)F

참가 물질

9

반응물 2

HCID 7151Methyl NicotinateHCID 89600919CID 89600919

생성물 3

HCID 83854590methyl 6-(difluoromethyl)nicotinate수율 14%HCID 971813862-Difluoromethyl-nicotinic acid methyl ester수율 14%HCID 97181391HCID 97181391, 화합물수율 18%

시약·촉매·용매 4

HCID 6410tert-Butyl hydroperoxide시약HCID 6422Trifluoroacetic acid시약HCID 962Water용매HCID 6344Dichloromethane용매

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온도
25 °C

출처 및 근거

ORD 기록
ord-e2d7b19e412b48f6a6b326f7f606bda6
출처 데이터셋
Minisci dataset from Roche

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