3-Chloro-6-methoxypyridazine → 3-Chloro-6-methoxy-4-propan-2-ylpyridazine

HRID 2418896노트

반응식

HRID 2418896 반응식
CC(C)S(=O)O.COc1ccc(Cl)nn1.[Zn]>CC(C)(C)OO.CS(C)=O.O>COc1cc(C(C)C)c(Cl)nn1.COc1nnc(Cl)cc1C(C)C

참가 물질

7

반응물 2

HCID 744033-Chloro-6-methoxypyridazineHCID 117778686Propane-2-sulfinic acid;ZINC

생성물 2

HCID 1350754806-Chloro-3-methoxy-4-propan-2-ylpyridazine수율 4%HCID 1624021723-Chloro-6-methoxy-4-propan-2-ylpyridazine수율 45%

시약·촉매·용매 3

HCID 6410tert-Butyl hydroperoxide시약HCID 679Dimethyl Sulfoxide용매HCID 962Water용매

반응 조건

온도
50 °C

출처 및 근거

ORD 기록
ord-0589f71f95eb4300a6f0870d4c0a9aa9
출처 데이터셋
Minisci dataset from Roche

반응 노트

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