Hydrochloric Acid → HCID 20313024, 화합물

HRID 2420109노트

반응식

HRID 2420109 반응식
[CH2:1]([C:8]1[CH:9]=[CH:10][C:11]([C:14]([OH:16])=[O:15])=[N:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[CH2:18](O)[CH3:19]>>[CH2:1]([C:8]1[CH:9]=[CH:10][C:11]([C:14]([O:16][CH2:18][CH3:19])=[O:15])=[N:12][CH:13]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 30428422-Pyridinecarboxylic acid, 5-(phenylmethyl)-

생성물 1

HCID 20313024HCID 20313024, 화합물

실험 절차

2.0 Grams of 5-benzylpicolinic acid were suspended in 25 ml. of ethanol. The resulting suspension was saturated with hydrogen chloride gas under ice-cooling. After reflux for three hours, the reaction solution was concentrated under reduced pressure. Ether was added thereto to form crystals. The crystals were then recrystallized from a solvent comprising a mixture of acetone/ether to obtain 1.7 g of ethyl 5-benzylpicolinate of a melting point of 109°~111° C.

후처리

  1. temperaturecooling
  2. temperatureAfter reflux for three hours
  3. concentrationthe reaction solution was concentrated under reduced pressure
  4. additionEther was added
  5. customto form crystals
  6. customThe crystals were then recrystallized from a solvent comprising
  7. additiona mixture of acetone/ether

출처 및 근거

ORD 기록
ord-60ae81fb857d426eba9005aab5bb7eeb
출처 데이터셋
uspto-grants-1978_08
특허 번호
US04109000

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