Phenol → 8-furfuryl-5-phenyloxy-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidine

HRID 2420583

반응식

HRID 2420583 반응식
[NH:1]([C:3]1[C:8]([C:9]([O:11][CH2:12][CH3:13])=O)=[CH:7][N:6]=[C:5]2[N:14]([CH2:17][C:18]3[O:22][CH:21]=[CH:20][CH:19]=3)[N:15]=[CH:16][C:4]=12)[NH2:2].[C:23]1(O)C=C[CH:26]=[CH:25][CH:24]=1>C(O)C>[CH2:17]([N:14]1[C:5]2[N:6]=[CH:7][C:8]3[C:9]([O:11][C:12]4[CH:26]=[CH:25][CH:24]=[CH:23][CH:13]=4)=[N:14][C:5]4[N:1]([N:2]=[CH:7][N:6]=4)[C:3]=3[C:4]=2[CH:16]=[N:15]1)[C:18]1[O:22][CH:21]=[CH:20][CH:19]=1

참가 물질

4

반응물 2

HCID 996PhenolHCID 867354024-Hydrazino-1-furfurylpyrazolo[3,4-b]pyridine-5-carboxylic acid, ethyl ester

생성물 1

HCID 227585308-furfuryl-5-phenyloxy-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidine

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

By substituting 4-hydrazino-1-furfurylpyrazolo[3,4-b]pyridine-5-carboxylic acid, ethyl ester for the 1-ethyl-4-hydrazino-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid,ethyl ester in Example 1 (a), 8-furfuryl-4H-pyrazolo[4',3'-5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-5(8H)-one is obtained. This compound is now processed as in Example 1 (b) and then as in Example 4, substituting phenol for the ethanol to obtain 8-furfuryl- 5-phenyloxy-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidine.

후처리

  1. customis obtained

출처 및 근거

ORD 기록
ord-348d79fc0701463f8a01efba56a045ff
출처 데이터셋
uspto-grants-1978_08
특허 번호
US04110454

연결된 노트

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