tert-Butanol → 3-(2-Tert-butoxy-2-oxoethoxy)-4-chlorobenzoic acid
반응식
[C:1]([O:5][C:6](=[O:20])[CH2:7][O:8][C:9]1[CH:10]=[C:11]([CH:16]=[CH:17][C:18]=1[Cl:19])[C:12]([O:14]C)=[O:13])([CH3:4])([CH3:3])[CH3:2].C(O)(C)(C)C>O>[C:1]([O:5][C:6](=[O:20])[CH2:7][O:8][C:9]1[CH:10]=[C:11]([CH:16]=[CH:17][C:18]=1[Cl:19])[C:12]([OH:14])=[O:13])([CH3:4])([CH3:2])[CH3:3]참가 물질
4
실험 절차
Methyl 3-(2-tert-butoxy-2-oxoethoxy)-4-chlorobenzoate (0.7 g) in 9:1 tert butanol:water was subjected to Antarctica B lipase for 6 d. Filtration and evaporation of the solvent yielded the subtitle compound as an off-white solid (0.6 g).
후처리
- filtrationFiltration and evaporation of the solvent
출처 및 근거
- ORD 기록
- ord-2a4a984cb75f44cda1ee1431d3326581
- 출처 데이터셋
- uspto-grants-2011_06
- 특허 번호
- US07956070B2
반응 노트
불러오는 중…