Hydrochloric Acid → 3-Bromo-8-iodo-quinolin-6-ylamine

HRID 2421534노트

반응식

HRID 2421534 반응식
[Br:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([CH:11]=1)=[CH:9][C:8]([N+:12]([O-])=O)=[CH:7][C:6]=2[I:15].Cl>[Fe]>[Br:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([CH:11]=1)=[CH:9][C:8]([NH2:12])=[CH:7][C:6]=2[I:15]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 672145383-Bromo-8-iodo-6-nitro-quinoline

생성물 1

HCID 672147063-Bromo-8-iodo-quinolin-6-ylamine

시약·촉매·용매 1

HCID 23925Iron촉매

실험 절차

In a similar procedure to Stage 1, Step 1 of Example 6, 3-bromo-8-iodo-6-nitro-quinoline was treated with concentrated hydrochloric acid and iron powder to give 3-bromo-8-iodo-quinolin-6-ylamine as a beige powder ((M+1)+ 351).

출처 및 근거

ORD 기록
ord-5d785e3a9d7c462b99a098b611e27805
출처 데이터셋
uspto-grants-2011_06
특허 번호
US07956188B2

반응 노트

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