Thionyl Chloride → 2-Chloro-2-oxoethyl 4'-chlorobiphenyl-4-sulfonate

HRID 2422925

반응식

HRID 2422925 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([S:14]([O:17][CH2:18][C:19]([OH:21])=O)(=[O:16])=[O:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.S(Cl)([Cl:24])=O>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([S:14]([O:17][CH2:18][C:19]([Cl:24])=[O:21])(=[O:16])=[O:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 86628700HCID 86628700, 화합물

생성물 1

HCID 866287022-Chloro-2-oxoethyl 4'-chlorobiphenyl-4-sulfonate

실험 절차

A mixture of acid 13 (100 mg, 0.306 mmol) and thionyl chloride (1 ml) was heated at reflux for 1.5 h. The excess thionyl chloride was removed in vacuo and the resulting pale yellow/white solid dried under high vacuum at 50° C. for 1.5 h. The product acid chloride 14 was used without further purification.

후처리

  1. temperaturewas heated
  2. temperatureat reflux for 1.5 h
  3. customThe excess thionyl chloride was removed in vacuo
  4. customthe resulting pale yellow/white solid dried under high vacuum at 50° C. for 1.5 h
  5. customThe product acid chloride 14 was used without further purification

출처 및 근거

ORD 기록
ord-d8e1d267abee4aeba70658dc436a7c38
출처 데이터셋
uspto-grants-2011_06
특허 번호
US07960434B2

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