4-Fluorobiphenyl → 4'-Fluorobiphenyl sulfonic acid

HRID 2425129노트

반응식

HRID 2425129 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.Cl[S:15]([OH:18])(=[O:17])=[O:16]>C(Cl)(Cl)Cl>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:13]([S:15]([OH:18])(=[O:17])=[O:16])=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:6][CH:7]=1

참가 물질

4

반응물 2

HCID 94614-FluorobiphenylHCID 24638Chlorosulfonic acid

생성물 1

HCID 181795134'-Fluorobiphenyl sulfonic acid

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

4′-Fluorobiphenyl (5 g) was dissolved in chloroform (100 mL) at room temperature. Chlorosulfonic acid (5 g) was added dropwise and stirring was continued for a further 4 hours, after which the solvent was allowed to slowly evaporate until precipitation was seen. The mixture was left to recrystallised overnight and the solid was collected by filtration. Further crops of crystals were collected from the filtrate.

후처리

  1. customto slowly evaporate until precipitation
  2. waitThe mixture was left
  3. customto recrystallised overnight
  4. filtrationthe solid was collected by filtration
  5. customFurther crops of crystals were collected from the filtrate

출처 및 근거

ORD 기록
ord-cac7a01dc1c048cab8ea26a96b5eb42f
출처 데이터셋
uspto-grants-2011_06
특허 번호
US07964643B2

반응 노트

불러오는 중…