Methylhydrazine → 1-Methyl-3-(trifluoromethyl)-1H-pyrazole
반응식
C(O[CH:4]=[CH:5][C:6](=O)[C:7]([F:10])([F:9])[F:8])C.[CH3:12][NH:13][NH2:14]>CO>[CH3:12][N:13]1[CH:4]=[CH:5][C:6]([C:7]([F:10])([F:9])[F:8])=[N:14]1참가 물질
4
실험 절차
To a mixture of 18 g of 4-ethoxy-1,1,1-trifluoro-3-butene-2-one and 50 ml of methanol was added 5.7 ml of methylhydrazine, and the mixture was heated to reflux for 4 hours. The reaction mixture was allowed to cool to room temperature, concentrated under reduced pressure, and subjected to distillation under reduced pressure (60° C./15 mmHg) to obtain 8.71 g of 1-methyl-3-trifluoromethyl-1H-pyrazole of the formula:
후처리
- temperaturethe mixture was heated
- temperatureto reflux for 4 hours
- concentrationconcentrated under reduced pressure
- distillationsubjected to distillation under reduced pressure (60° C./15 mmHg)
출처 및 근거
- ORD 기록
- ord-87ab800a8452418e8d11e0a88bc6da28
- 출처 데이터셋
- uspto-grants-2011_06
- 특허 번호
- US07968573B2
반응 노트
불러오는 중…